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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP10 All Species: 18.18
Human Site: S464 Identified Species: 33.33
UniProt: Q14694 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14694 NP_005144.2 798 87134 S464 T S T P M I D S F V R L M N E
Chimpanzee Pan troglodytes XP_511147 902 98075 S590 T S T P M I D S F V R L M N E
Rhesus Macaque Macaca mulatta XP_001111197 930 101558 S596 T S T P M I D S F V R L M N E
Dog Lupus familis XP_536761 834 90976 S500 T S T P M I D S F V R L M N E
Cat Felis silvestris
Mouse Mus musculus P52479 792 87004 E465 S F V R L M N E F T N M P V P
Rat Rattus norvegicus Q3KR59 794 87293 S460 T S T P M I D S F V R L M N E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510486 793 87073 V471 N E F T N M P V P S K A K Q A
Chicken Gallus gallus Q5ZJN4 785 86537 V463 N E F T N M P V P P K A K Q A
Frog Xenopus laevis Q2NL57 791 87545 E464 S F V R L M N E F T N M P I L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122220 379 42828 P69 K F V H E F T P L S D G A R L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794239 817 88996 M476 S T P M L D A M Y K F L K E F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FPS3 551 60422 L241 P K A D S P T L A A F S E F I
Baker's Yeast Sacchar. cerevisiae Q01477 912 101898 D509 T S S C K L L D A C L T M Y K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.4 84.4 85.4 N.A. 83.3 84.2 N.A. 79.6 78.5 70.5 N.A. N.A. N.A. 24.4 N.A. 36.6
Protein Similarity: 100 85.6 85.1 89 N.A. 88.8 88.7 N.A. 86.9 84.3 79.3 N.A. N.A. N.A. 35.5 N.A. 52.8
P-Site Identity: 100 100 100 100 N.A. 6.6 100 N.A. 0 0 6.6 N.A. N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 40 100 N.A. 13.3 13.3 40 N.A. N.A. N.A. 0 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 25.5 22.8 N.A.
Protein Similarity: N.A. N.A. N.A. 43.8 40.7 N.A.
P-Site Identity: N.A. N.A. N.A. 0 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 8 0 16 8 0 16 8 0 16 % A
% Cys: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 8 39 8 0 0 8 0 0 0 0 % D
% Glu: 0 16 0 0 8 0 0 16 0 0 0 0 8 8 39 % E
% Phe: 0 24 16 0 0 8 0 0 54 0 16 0 0 8 8 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 39 0 0 0 0 0 0 0 8 8 % I
% Lys: 8 8 0 0 8 0 0 0 0 8 16 0 24 0 8 % K
% Leu: 0 0 0 0 24 8 8 8 8 0 8 47 0 0 16 % L
% Met: 0 0 0 8 39 31 0 8 0 0 0 16 47 0 0 % M
% Asn: 16 0 0 0 16 0 16 0 0 0 16 0 0 39 0 % N
% Pro: 8 0 8 39 0 8 16 8 16 8 0 0 16 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 16 0 % Q
% Arg: 0 0 0 16 0 0 0 0 0 0 39 0 0 8 0 % R
% Ser: 24 47 8 0 8 0 0 39 0 16 0 8 0 0 0 % S
% Thr: 47 8 39 16 0 0 16 0 0 16 0 8 0 0 0 % T
% Val: 0 0 24 0 0 0 0 16 0 39 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _